Simultaneous Determination of Aceclofenac, Paracetamol and Chlorzoxazone by HPLC in Tablet Dose Form
نویسندگان
چکیده
منابع مشابه
Simultaneous Estimation of Paracetamol, Chlorzoxazone and Aceclofenac in Pharmaceutical Formulation by Hplc Method
A rapid and sensitive high performance liquid chromatography with UV detection method was developed and validated for the quantification of paracetamol, chlorzoxazone and aceclofenac in dosage forms. The chromatographic separation was carried out on a Phenomenex Luna C18 column using a mixture of acetonitrile-0.05M disodium hydrogen orthophosphate (65:35) (pH adjusted to 3.0 using 10% orthophos...
متن کاملReverse Phase HPLC Method for Determination of Aceclofenac and Paracetamol in Tablet Dosage Form
1. Sweetman S. C., Eds, In; Martindale ‘The complete drug reference, 33rd Edn., The Pharmaceutical Press, London, 2002, 209. 2. Perry, C.M., Barman Balfour, J.A. and Lamb, H.M., Drugs., 1999, 58, 683. 3. Lawrence M. T., Stephen J. .M., Maxine A.P., Current Medical Diagnosis and Treatment., 42nd Edn., The McGraw Hill Companies, Inc. India, 2003, 1525. TABLE 1: RESULTS OF ANALYSIS AND RECOVERY ST...
متن کاملApplication of HPLC for the Simultaneous Determination of Aceclofenac, Paracetamol and Tramadol Hydrochloride in Pharmaceutical Dosage Form
A simple, precise and accurate reversed-phase liquid chromatographic method has been developed for the simultaneous estimation of aceclofenac (ACF), paracetamol (PCM) and tramadol hydrochloride (TRM) in pharmaceutical dosage form. The chromatographic separation was achieved on a HiQ-Sil™ HS C18 column (250×4.6 mm i.d., 5 μm particle size), kromatek analytical column at ambient temperature. The ...
متن کاملSimultaneous determination of paracetamol and lornoxicam by RP-HPLC in bulk and tablet formulation
AIM The objective of the study was to develop simple RP-HPLC method for the simultaneous determination of paracetamol and lornoxicam without prior separation. MATERIALS AND METHODS In this method, Kromasil C8 (250 mm, 4.6 mm, 5 μm) column was used. The mobile phase used was methanol:phosphate buffer (60:40, v/v, pH 6.4), at flow rate of 1 ml min(-1). UV detection was monitored at 302 nm. RE...
متن کاملSimultaneous Spectrophotometric Determination of Drotaverine Hydrochloride and Paracetamol in Tablet
Two simple, accurate and reproducible spectrophotometric methods; Q analysis and first order derivative method have been described for the simultaneous estimation of drotaverine hydrochloride and paracetamol in combined tablet dosage form. Absorption maxima of drotaverine hydrochloride and paracetamol in distilled water were found to be 303.5 nm and 243.5 nm respectively. Beer's law was obeyed ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: E-Journal of Chemistry
سال: 2009
ISSN: 0973-4945,2090-9810
DOI: 10.1155/2009/139484